MRX-2843 [1429882-07-4]
T16144
CAS Number1429882-07-4
Product group Chemicals
Estimated Purity99.51%
Molecular Weight488.67
Overview
- SupplierTargetMol Chemicals
- Product NameMRX-2843 [1429882-07-4]
- Delivery Days Customer9
- CAS Number1429882-07-4
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameMRX-2843
- Estimated Purity99.51%
- Molecular FormulaC29H40N6O
- Molecular Weight488.67
- Scientific DescriptionMRX-2843 (UNC2371) is a potent and orally active inhibitor of MERTK and FLT3(IC50s of 1.3 nM and 0.64 nM, respectively).
- Shelf life instruction3 years
- SMILESCN1CCN(Cc2ccc(cc2)-c2cn([C@H]3CC[C@H](O)CC3)c3nc(NCCC4CC4)ncc23)CC1
- Storage Instruction-20°C
- UNSPSC12352200
References
- The MERTK/FLT3 inhibitor MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemia. Minson KA et al., 2016 Mar, JCI InsightRead more
