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MRX-2843 [1429882-07-4]

MRX-2843 [1429882-07-4]

T16144
TargetMol Chemicals
CAS Number1429882-07-4
Product group Chemicals
Estimated Purity99.51%
Molecular Weight488.67
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    MRX-2843 [1429882-07-4]
  • Delivery Days Customer
    9
  • CAS Number
    1429882-07-4
  • Certification
    Research Use Only
  • Chemical Name
    MRX-2843
  • Estimated Purity
    99.51%
  • Molecular Formula
    C29H40N6O
  • Molecular Weight
    488.67
  • Scientific Description
    MRX-2843 (UNC2371) is a potent and orally active inhibitor of MERTK and FLT3(IC50s of 1.3 nM and 0.64 nM, respectively).
  • Shelf life instruction
    3 years
  • SMILES
    CN1CCN(Cc2ccc(cc2)-c2cn([C@H]3CC[C@H](O)CC3)c3nc(NCCC4CC4)ncc23)CC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Minson KA, Smith CC, DeRyckere D, et al. The MERTK/FLT3 inhibitor MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemia. JCI Insight. 2016,1(3):e85630. doi: 10.1172/jci.insight.85630
    Read this paper

MSDS

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