MS4078

MedChem Express

MS4078 [2229036-62-6]

10

2229036-62-6

Research Use Only

99.72

C45H52ClN9O8S

914.47

MS4078 is an anaplastic lymphoma kinase ( ALK ) PROTAC (degrader) based on Cereblon ligand, with a K d of 19?nM for binding affinity to ALK [1] .

CC(C)S(C1=C(NC2=NC(NC3=C(OC(C)C)C=C(C4CCN(CC(NCCNC5=C(C(N(C6C(NC(CC6)=O)=O)C7=O)=O)C7=CC=C5)=O)CC4)C(C)=C3)=NC=C2Cl)C=CC=C1)(=O)=O

-20°C,2°C to 8°C

12352200