Bio-Connect

MS8511 (hydrochloride)

HY-150510A
MedChem Express
Estimated Purity98.0
Product group Chemicals
Molecular Weight532.12
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MS8511 (hydrochloride) [3031788-28-7]
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Estimated Purity
    98.0
  • Molecular Formula
    C28H42ClN5O3
  • Molecular Weight
    532.12
  • Scientific Description
    MS8511 (hydrochloride) is a selective G9a/GLP covalent irreversible inhibitor by targeting a cysteine residue at the substrate binding site, with IC50 values of 100 nM (G9a) and 140 nM (GLP), and Kd values of 44 nM (G9a) and 46 nM (GLP). MS8511 (hydrochloride) reduces the cellular H3K9me2 level and enhances antiproliferation activity. MS8511 (hydrochloride) can be used for the research of several types of cancers including brain, breast, ovarian, lung, bladder, melanoma, colorectal cancer, and other disease such as Alzheimers disease (AD), sickle cell disease, Prader-Willi syndrome (PWS)[1].
  • SMILES
    COC1=CC(C(C=C1OCCCN2CCCC2)=NC(NC(C=C)=O)=C3)=C3NC4CCN(CC4)C(C)C.Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12131703