MS8511 (hydrochloride)
HY-150510A
Overview
- SupplierMedChem Express
- Product NameMS8511 (hydrochloride) [3031788-28-7]
- Delivery Days Customer5
- CertificationResearch Use Only
- Estimated Purity98.0
- Molecular FormulaC28H42ClN5O3
- Molecular Weight532.12
- Scientific DescriptionMS8511 (hydrochloride) is a selective G9a/GLP covalent irreversible inhibitor by targeting a cysteine residue at the substrate binding site, with IC50 values of 100 nM (G9a) and 140 nM (GLP), and Kd values of 44 nM (G9a) and 46 nM (GLP). MS8511 (hydrochloride) reduces the cellular H3K9me2 level and enhances antiproliferation activity. MS8511 (hydrochloride) can be used for the research of several types of cancers including brain, breast, ovarian, lung, bladder, melanoma, colorectal cancer, and other disease such as Alzheimers disease (AD), sickle cell disease, Prader-Willi syndrome (PWS)[1].
- SMILESCOC1=CC(C(C=C1OCCCN2CCCC2)=NC(NC(C=C)=O)=C3)=C3NC4CCN(CC4)C(C)C.Cl
- Storage Instruction-20°C
- UNSPSC12131703