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ProductsBack/MSH2 antibody [G219-1129]

MSH2 antibody [G219-1129]

Research Use Only
GTX01748
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetMSH2
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Overview

  • Supplier
    GeneTex
  • Product Name
    MSH2 antibody [G219-1129]
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    G219-1129
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID4436
  • Target name
    MSH2
  • Target description
    mutS homolog 2
  • Target synonyms
    COCA1; DNA mismatch repair protein Msh2; DNA mismatch repair protein Msh2 transcript; FCC1; hMSH2; HNPCC; HNPCC1; LCFS2; MMRCS2; mutS homolog 2, colon cancer, nonpolyposis type 1
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP43246
  • Protein Name
    DNA mismatch repair protein Msh2
  • Scientific Description
    This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • A Novel Germline MLH1 In-Frame Deletion in a Slovenian Lynch Syndrome Family Associated with Uncommon Isolated PMS2 Loss in Tumor Tissue. Klancar G et al., 2020 Mar 18, Genes (Basel)
    Read more
  • Inflammation-Associated Microsatellite Alterations Caused by MSH3 Dysfunction Are Prevalent in Ulcerative Colitis and Increase With Neoplastic Advancement. Munakata K et al., 2019 Dec, Clin Transl Gastroenterol
    Read more
  • Screening for microsatellite instability in colorectal carcinoma: Practical utility of immunohistochemistry and PCR with fragment analysis in a diagnostic histopathology setting. Cheah PL et al., 2019 Aug, Malays J Pathol
    Read more
  • Molecular classification of endometrial carcinoma applied to endometrial biopsy specimens: Towards early personalized patient management. Abdulfatah E et al., 2019 Sep, Gynecol Oncol
    Read more
  • Coping with formalin banning in pathology: under vacuum long-term tissue storage with no added formalin. Mastracci L et al., 2019 Jun, Histochem Cell Biol
    Read more