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ProductsBack/MSH6 antibody

MSH6 antibody

GTX16574
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetMSH6
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Overview

  • Supplier
    GeneTex
  • Product Name
    MSH6 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 0.5-1 microg/ml. ICC/IF: 10-20 microg/ml. IP: 2.5-5 microg. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID2956
  • Target name
    MSH6
  • Target description
    mutS homolog 6
  • Target synonyms
    DNA mismatch repair protein Msh6; G/T mismatch-binding protein; GTBP; GTMBP; HNPCC5; HSAP; MMRCS3; mutS protein homolog 6; mutS-alpha 160 kDa subunit; p160; sperm-associated protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP52701
  • Protein Name
    DNA mismatch repair protein Msh6
  • Scientific Description
    Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. it is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203