Western Blot Positive WB detected in: U251 whole cell lysate All lanes: MSL2 antibody at 5microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 63, 55 kDa Observed band size: 63 kDa
Western Blot Positive WB detected in: U251 whole cell lysate All lanes: MSL2 antibody at 5microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 63, 55 kDa Observed band size: 63 kDa
MSL2 Antibody
CSB-PA875722LA01HU
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetMSL2
Overview
- SupplierCusabio
- Product NameMSL2 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID55167
- Target nameMSL2
- Target descriptionMSL complex subunit 2
- Target synonymsE3 ubiquitin-protein ligase MSL2; E3 ubiquitin-protein transferase MSL2; male-specific lethal 2 homolog; male-specific lethal 2-like 1; male-specific lethal-2 homolog 1; MSL-2; MSL2L1; MSL2-like 1; ring finger protein 184; RNF184
- HostRabbit
- IsotypeIgG
- Protein IDQ9HCI7
- Protein NameE3 ubiquitin-protein ligase MSL2
- Scientific DescriptionComponent of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at Lys-35 (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at Lys-4 (H3K4me) and Lys-79 (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203