MTase-IN-1

MedChem Express

MTase-IN-1

14

Research Use Only

C31H29N7O6S

627.67

MTase-IN-1 (compound 26) is a potent and selective inhibitor of coronavirus nsp14 N7-methyltransferases, with an IC50 of 0.72 nM. MTase-IN-1 impairs viral RNA translation and immune evasion[1].

O[C@H]1[C@@H](O)[C@H](N2C(N=CN=C3N)C3C(C#CC4=CN=C(C=CC=C5)C5=C4)=C2)O[C@@H]1CN(S(C6=CC=C(OC)C(C#N)=C6)(=O)=O)C

12352200