ELISA analysis of antigen using GTX60435 MTHFR antibody [5D3]. Red : Control antigen 100ng Purple : Antigen 10ng Green : Antigen 50ng Blue : Antigen 100ng
![IHC-P analysis of lung cancer using GTX60435 MTHFR antibody [5D3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX60435/GTX60435_20170912_IHC-P_1_w_23061123_621.webp "IHC-P analysis of lung cancer using GTX60435 MTHFR antibody [5D3].")
![IHC-P analysis of intima cancer tissue (left) and prostate tissue (right) using GTX60435 MTHFR antibody [5D3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX60435/GTX60435_20170912_IHC-P_w_23061123_313.webp "IHC-P analysis of intima cancer tissue (left) and prostate tissue (right) using GTX60435 MTHFR antibody [5D3].")
![WB analysis of Rat heart tissue lysate using GTX60435 MTHFR antibody [5D3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX60435/GTX60435_20170912_WB_1_w_23061123_132.webp "WB analysis of Rat heart tissue lysate using GTX60435 MTHFR antibody [5D3].")
![WB analysis of HEK293 (1) and MTHFR(AA: 339-499)-hIgGFc transfected HEK293 (2) cell lysate using GTX60435 MTHFR antibody [5D3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX60435/GTX60435_20170912_WB_w_23061123_711.webp "WB analysis of HEK293 (1) and MTHFR(AA: 339-499)-hIgGFc transfected HEK293 (2) cell lysate using GTX60435 MTHFR antibody [5D3].")
ELISA analysis of antigen using GTX60435 MTHFR antibody [5D3]. Red : Control antigen 100ng Purple : Antigen 10ng Green : Antigen 50ng Blue : Antigen 100ng
MTHFR antibody [5D3]
GTX60435
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetMTHFR
Overview
- SupplierGeneTex
- Product NameMTHFR antibody [5D3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1/500 - 1/2000. IHC-P: 1/200 - 1/1000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID5D3
- ConjugateUnconjugated
- Gene ID4524
- Target nameMTHFR
- Target descriptionmethylenetetrahydrofolate reductase
- Target synonymsmethylenetetrahydrofolate reductase (NADPH), 5,10-methylenetetrahydrofolate reductase (NADPH), methylenetetrahydrofolate reductase (NAD(P)H)
- HostMouse
- IsotypeIgG1
- Protein IDP42898
- Protein NameMethylenetetrahydrofolate reductase (NADPH)
- Scientific DescriptionThe protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Gajjar KK, Vora HH, Kobawala TP, et al. Deciphering the potential value of 5-fluorouracil metabolic enzymes in predicting prognosis and treatment response of colorectal cancer patients. Int J Biol Markers. 2018,33(2):180-188. doi: 10.1177/1724600817748539Read this paper
Datasheet
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