MTK458 [2499962-58-0]

MedChem Express

MTK458 [2499962-58-0]

5

2499962-58-0

Research Use Only

99.28

C17H15F3N4

332.32

MTK458 is an orally active brain penetrant PINK1 activator. MTK458 binds to PINK1 and stabilizes an active heterocomplex, thereby increasing mitophagy. MTK458 can be used for research on Parkinsons disease[1].

FC(F)(F)C1=CC(C(N1)=NC=N2)=C2N[C@H]3C4=CC=CC=C4CCC3

2°C to 8°C

12352200