mTOR inhibitor-2 [2219323-96-1]

MedChem Express

mTOR inhibitor-2 [2219323-96-1]

10

2219323-96-1

Research Use Only

C23H21N7O

411.46

mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates[1].

O=C(N1C2CCN(CC#N)CC2)C=NC3=C1C4=CC(C5=CN=C(N)C=C5)=CC=C4N=C3

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