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mTOR inhibitor WYE-28 [1062172-60-4]

HY-118717
MedChem Express
CAS Number1062172-60-4
Product group Chemicals
Estimated Purity99.75
Molecular Weight586.64
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Overview

  • Supplier
    MedChem Express
  • Product Name
    mTOR inhibitor WYE-28 [1062172-60-4]
  • Delivery Days Customer
    14
  • CAS Number
    1062172-60-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.75
  • Molecular Formula
    C30H34N8O5
  • Molecular Weight
    586.64
  • Scientific Description
    mTOR inhibitor WYE-28 (compound 28) is a selective inhibitor of mTOR>/bIC50)=0.08 nM. mTOR inhibitor WYE-28 inhibits PI3Kalpha with an IC50 value of 6 nM. mTOR inhibitor WYE-28 shows a metabolic time (T1/2) in nude mouse microsomes of 13 min[1].
  • SMILES
    O=C(N1CCC(N2N=CC3=C(N=C(N=C32)C4=CC=C(C=C4)NC(NC5=CC=C(C=C5)CO)=O)N6CCOCC6)CC1)OC
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200