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mtPAP antibody [1D3]

Name: mtPAP antibody [1D3]
SKU: GTX70156_G10
Availability: BackOrder

GTX70156

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetMTPAP

Overview

Supplier
GeneTex
Product Name
mtPAP antibody [1D3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
1D3
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID55149
Target name
MTPAP
Target description
mitochondrial poly(A) polymerase
Target synonyms
PAPD1, SPAX4, TENT6, poly(A) RNA polymerase, mitochondrial, PAP-associated domain-containing protein 1, TUTase 1, polynucleotide adenylyltransferase, terminal uridylyltransferase 1
Host
Mouse
Isotype
IgG1
Protein IDQ9NVV4
Protein Name
Poly(A) RNA polymerase, mitochondrial
Scientific Description
The protein encoded by this gene is a member of the DNA polymerase type-B-like family. This enzyme synthesizes the 3 poly(A) tail of mitochondrial transcripts and plays a role in replication-dependent histone mRNA degradation.[provided by RefSeq, Jan 2011]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Van Eyck L, Bruni F, Ronan A, et al. Biallelic Mutations in MTPAP Associated with a Lethal Encephalopathy. Neuropediatrics. 2020,51(3):178-184. doi: 10.1055/s-0039-3400979
Read this paper
Wilson WC, Hornig-Do HT, Bruni F, et al. A human mitochondrial poly(A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression. Hum Mol Genet. 2014,23(23):6345-55. doi: 10.1093/hmg/ddu352
Read this paper