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mtPAP antibody [1D3]

GTX70156
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetMTPAP
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Overview

  • Supplier
    GeneTex
  • Product Name
    mtPAP antibody [1D3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1D3
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID55149
  • Target name
    MTPAP
  • Target description
    mitochondrial poly(A) polymerase
  • Target synonyms
    PAP-associated domain-containing protein 1; PAPD1; poly(A) RNA polymerase, mitochondrial; polynucleotide adenylyltransferase; SPAX4; TENT6; terminal uridylyltransferase 1; TUTase 1
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDQ9NVV4
  • Protein Name
    Poly(A) RNA polymerase, mitochondrial
  • Scientific Description
    The protein encoded by this gene is a member of the DNA polymerase type-B-like family. This enzyme synthesizes the 3 poly(A) tail of mitochondrial transcripts and plays a role in replication-dependent histone mRNA degradation.[provided by RefSeq, Jan 2011]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Biallelic Mutations in MTPAP Associated with a Lethal Encephalopathy. Van Eyck L et al., 2020 Jun, Neuropediatrics
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  • A human mitochondrial poly(A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression. Wilson WC et al., 2014 Dec 1, Hum Mol Genet
    Read more