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mtRNA polymerase antibody [N2N3]

GTX105137
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetPOLRMT
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Overview

  • Supplier
    GeneTex
  • Product Name
    mtRNA polymerase antibody [N2N3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5442
  • Target name
    POLRMT
  • Target description
    RNA polymerase mitochondrial
  • Target synonyms
    APOLMT; DNA-directed RNA polymerase, mitochondrial; h-mtRPOL; MTRNAP; MTRPOL; polymerase (RNA) mitochondrial (DNA directed)
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO00411
  • Protein Name
    DNA-directed RNA polymerase, mitochondrial
  • Scientific Description
    This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Unexpected conformational variations of the human centromeric chromatin complex. Thakur J et al., 2018 Jan 1, Genes Dev
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  • Non-B-Form DNA Is Enriched at Centromeres. Kasinathan S et al., 2018 Apr 1, Mol Biol Evol
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  • Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I. Sobek S et al., 2013 Nov, Nucleic Acids Res
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