MTX-241F

MedChem Express

MTX-241F

14

Research Use Only

C20H14ClFN6

392.82

MTX-241F is a selective small molecule inhibitor targeting EGFR and PI3 kinase family members. MTX-241F is able to penetrate the blood-brain barrier and control tumor growth over the long term. MTX-241F exhibits radiosensitizing activity in patient-derived DIPG neurospheres and may be used in the study of diffuse intrinsic pontine glioma (DIPG)[1].

NC1=NC=C(C2=CC=C(N=CN=C3N4C5=CC(Cl)=C(F)C=C5CC4)C3=C2)C=N1

12131703