MUC18 / Mucin 18 / CD146(MUC18/1130), CF405S conjugate, 0.1mg/mL [26628-22-8]

Biotium

MUC18 / Mucin 18 / CD146(MUC18/1130), CF405S conjugate, 0.1mg/mL [26628-22-8]

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

MUC18/1130

0.1 mg/ml

Other Conjugate

MCAM

melanoma cell adhesion molecule

CD146, HEMCAM, METCAM, MUC18, MelCAM, cell surface glycoprotein MUC18, Gicerin, S-endo 1 endothelial-associated antigen, cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma-associated antigen A32, melanoma-associated antigen MUC18

Mouse

IgG1

Cell surface glycoprotein MUC18

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Human, Mouse

2°C to 8°C

12352203