Mucin 5AC (MUC5AC)(45M1), CF405S conjugate, 0.1mg/mL [26628-22-8]

Biotium

Mucin 5AC (MUC5AC)(45M1), CF405S conjugate, 0.1mg/mL

9

Flow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

45M1

0.1 mg/ml

Other Conjugate

MUC5AC

mucin 5AC, oligomeric mucus/gel-forming

gastric mucin; leB; lewis B blood group antigen; major airway glycoprotein; MUC5; mucin; mucin 5, subtypes A and C, tracheobronchial/gastric; mucin 5AC, oligomeric mucus/gel-forming pseudogene; mucin-5 subtype AC, tracheobronchial; mucin-5AC; TBM; tracheobronchial mucin

Mouse

IgG1

Mucin-5AC

This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. The epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Chicken, Feline, Hedgehog, Human, Monkey, Mouse, Porcine, Rabbit, Rat

2°C to 8°C

12352203