Bio-Connect

Multi-kinase-IN-2 [2095628-21-8]

HY-150026
MedChem Express
CAS Number2095628-21-8
Product group Chemicals
Molecular Weight561.67
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    Multi-kinase-IN-2 [2095628-21-8]
  • Delivery Days Customer
    10
  • CAS Number
    2095628-21-8
  • Certification
    Research Use Only
  • Molecular Formula
    C34H35N5O3
  • Molecular Weight
    561.67
  • Scientific Description
    Multi-kinase-IN-2 (compound 7h) is an orally active and potent angiokinase inhibitor. Multi-kinase-IN-2 exhibits excellent inhibitory activity against angiokinases including VEGFR-1/2/3, PDGFRalpha/beta, and FGFR-1, as well as LYN and c-KIT kinases. Multi-kinase-IN-2 significantly attenuates phosphorylation of AKT and ERK proteins. Multi-kinase-IN-2 induces cell apoptosis. Multi-kinase-IN-2 shows anticancer activity[1].
  • SMILES
    O=C(C1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(N4C(C)=CC=C4CN5CCN(C)CC5)C=C3)/C6=CC=CC=C6)OC
  • UNSPSC
    12131703