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ProductsBack/Muscarinic Acetylcholine Receptor (mAChR) M5/NFAT Luciferase Reporter HEK293 Cell Line

Muscarinic Acetylcholine Receptor (mAChR) M5/NFAT Luciferase Reporter HEK293 Cell Line

82729
BPS Bioscience
CategoryCell Culture
Product group Cell Culture
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    Muscarinic Acetylcholine Receptor (mAChR) M5/NFAT Luciferase Reporter HEK293 Cell Line
  • Delivery Days Customer
    23
  • Certification
    Research Use Only
  • Scientific Description
    The Muscarinic Acetylcholine Receptor (mAChR) M5/NFAT Luciferase Reporter HEK293 Cell Line is a HEK293 cell line stably expressing the full-length human muscarinic acetylcholine receptor M5 (CHRM5/HM5/M5; accession number: AF498919) and a firefly luciferase reporter under the control of the NFAT (nuclear factor of activated T cells) response element. This cell line has been validated by flow cytometry and for its responses to the muscarinic acetylcholine receptor agonists Oxotremorine M and Carbamoylcholine chloride (carbachol). Luciferase activity increases in proportion to mAChR activation. Figure 1: Diagram illustrating the mechanism of action of Muscarinic Acetylcholine Receptor (mAChR) M5/NFAT Luciferase Reporter HEK293 Cell Line. Interested in screening and profiling inhibitors, blocking antibodies, or activators of M5 related signaling without the need to purchase and license the cell line? Check out our Cell Signaling Pathway Screening.
  • Storage Instruction
    Liquid Nitrogen
  • UNSPSC
    12352207