Mutant IDH1-IN-1 [1355326-21-4]

MedChem Express

Mutant IDH1-IN-1 [1355326-21-4]

10

1355326-21-4

Research Use Only

99.43

C30H31FN4O2

498.59

Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively.

O=C(C(C1=C(C)C=CC=C1)N(C(CN2C=NC3=C2C=CC=C3)=O)C4=CC(F)=CC=C4)NC5CCCCC5

-20°C,2°C to 8°C

12131703