Mutant IDH1-IN-2
HY-18717
CAS Number1429176-69-1
Product group Chemicals
Estimated Purity98.50
Molecular Weight459.53
Overview
- SupplierMedChem Express
- Product NameMutant IDH1-IN-2 [1429176-69-1]
- Delivery Days Customer10
- CAS Number1429176-69-1
- CertificationResearch Use Only
- Estimated Purity98.50
- Molecular FormulaC24H31F2N5O2
- Molecular Weight459.53
- Scientific DescriptionMutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS-MS biochemical assay, IC50 of 16.6 nM in Fluorescence biochemical assay. Target: Mutant IDH1 Mutant IDH1-IN-2 has a neomorphic activity and in the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer. More bioactivity information in Patent WO 2013046136A1 (Example 224).
- SMILESO=C1OC[C@H](C(C)C)N1C2=NC(N[C@H](C3=CC=C(CN4CCC(F)(F)CC4)C=C3)C)=NC=C2
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200