MyD88 antibody, Internal

GeneTex

MyD88 antibody, Internal

7

This antibody is expected to recognize reported isoforms 1, 2 and 3 (NP_001166038.1; NP_002459.2; NP_001166039.1).

WB: 0.1-0.3microg/ml. IHC-P: 4-6microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

MYD88

MYD88 innate immune signal transduction adaptor

IMD68; mutant myeloid differentiation primary response 88; MYD88D; myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response protein MyD88

Goat

IgG

Myeloid differentiation primary response protein MyD88

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Human

-20°C or -80°C,2°C to 8°C

12352203