IHC image of CSB-PA856414LA01HU diluted at 1:200 and staining in paraffin-embedded human glioma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA856414LA01HU diluted at 1:200 and staining in paraffin-embedded human glioma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
MYO18A Antibody
CSB-PA856414LA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetMYO18A
Overview
- SupplierCusabio
- Product NameMYO18A Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID399687
- Target nameMYO18A
- Target descriptionmyosin XVIIIA
- Target synonymsMAJN, MYSPDZ, SP-R210, SPR210, TIAF1, unconventional myosin-XVIIIa, 12 kDa TGF-beta-1-induced antiapoptotic factor, Putative TGFB1-induced anti-apoptotic factor 1, SP-A receptor subunit SP-R210 alphaS, TGF-beta-1-induced antiapoptotic factor 1, TGFB1-induced anti-apoptotic factor 1, molecule associated with JAK3 N-terminus, molecule associated with Jak-3 N-terminal, myosin 18A, myosin containing PDZ domain, myosin containing a PDZ domain, surfactant protein receptor SP-R210
- HostRabbit
- IsotypeIgG
- Protein IDQ92614
- Protein NameUnconventional myosin-XVIIIa
- Scientific DescriptionMay link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035, PubMed:23345592). Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking (PubMed:25965346). Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages (PubMed:16087679, PubMed:21123169). Strongly enhances natural killer cell cytotoxicity (PubMed:27467939).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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