Myriocin [35891-70-4]

MedChem Express

Myriocin [35891-70-4]

10

35891-70-4

Research Use Only

99.0

C21H39NO6

401.54

Myriocin (Thermozymocidin), a fungal metabolite could be isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 microg/mL for inhibiting HCV infection[1][2][3].

CCCCCCC(CCCCCC/C=C/C[C@@H](O)[C@H](O)[C@](CO)(N)C(O)=O)=O

-20°C

12352200