MYSM1 antibody

GeneTex

MYSM1 antibody

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

MYSM1

Myb like, SWIRM and MPN domains 1

2ADUB; 2A-DUB; BMFS4; deubiquitinase MYSM1; histone H2A deubiquitinase MYSM1; myb-like, SWIRM and MPN domain-containing protein 1

Rabbit

IgG

Histone H2A deubiquitinase MYSM1

Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.

Human

-20°C or -80°C,2°C to 8°C

12352203