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MYST2 antibody [N2C1], Internal

GTX102041
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetKAT7
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Overview

  • Supplier
    GeneTex
  • Product Name
    MYST2 antibody [N2C1], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.33 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID11143
  • Target name
    KAT7
  • Target description
    lysine acetyltransferase 7
  • Target synonyms
    HBO1; HBOA; histone acetyltransferase binding to ORC1; histone acetyltransferase KAT7; histone acetyltransferase MYST2; K(lysine) acetyltransferase 7; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; MYST histone acetyltransferase 2; MYST2; ZC2HC7
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO95251
  • Protein Name
    Histone acetyltransferase KAT7
  • Scientific Description
    Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1. Wright DG et al., 2016 Jan 12, Oncotarget
    Read more

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