N-Acetyl-Calicheamicin

MedChem Express

N-Acetyl-Calicheamicin [108212-76-6]

10

108212-76-6

Research Use Only

99.39

C57H76IN3O22S4

1410.39

N-Acetyl-Calicheamicin (N-Acetyl-Calicheamicin gamma), an enediyne anti-tumor antibiotic , is an ADC cytotoxin . N-Acetyl-Calicheamicin can induce DNA damage, and can be used in the synthesis of ADC [1] .

O[C@](CC1=O)(C#C/C=C\C#C2)/C(C([C@H]2O[C@@](O[C@H](C)[C@@H](NO[C@H](O[C@H](C)[C@H]3SC(C(C(C)=C(I)C(O[C@H](O[C@@H](C)[C@H](O)[C@H]4OC)[C@@H]4O)=C5OC)=C5OC)=O)C[C@@H]3O)[C@@H]6O)([H])[C@@H]6O[C@@](OC[C@@H]7N(CC)C(C)=O)([H])C[C@@H]7OC)=C1NC(OC)=O)=C/CSSSC

2°C to 8°C

12352200