N-Arachidonoyl Taurine [119959-65-8]

TargetMol Chemicals

N-Arachidonoyl Taurine [119959-65-8]

44

119959-65-8

Research Use Only

N-Arachidonoyl Taurine

C22H37NO4S

411.6

N-Arachidonoyl taurine is an arachidonoyl amino acid. It is oxygenated by 12(S)- and 15(S)-lipoxygenase and is converted to 12-HETE-taurine (12-HETE-T) in murine resident peritoneal macrophages. N-Arachidonoyl taurine is an activator of the transient receptor potential vanilloid (TRPV) channels TRPV1 and TRPV4 (EC50s = 28 and 21 microM, respectively). It increases calcium flux in HIT-T15 pancreatic beta-cells and INS-1 rat islet cells when used at a concentration of 10 microM and increases insulin secretion from 832/13 INS-1 pancreatic beta-cells. The levels of N-arachidonoyl taurine are changed in mouse brain following administration of delta9-tetrahydrocannabinol (delta9-THC).

3 years

CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCS(O)(=O)=O

-20°C

12352200