N-Boc-8-amino-octanoic acid [30100-16-4]

MedChem Express

N-Boc-8-amino-octanoic acid [30100-16-4]

5

30100-16-4

Research Use Only

97.0

C13H25NO4

259.34

N-Boc-8-amino-octanoic acid (Boc-8-aminooctanoic acid) can be used as a PROTAC linker in the synthesis of PROTACs. N-Boc-8-amino-octanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

O=C(O)CCCCCCCNC(OC(C)(C)C)=O

RT

41115800