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N-Deacetylcolchicine

ORB2283066
Biorbyt
CAS Number3476-50-4
Product group Chemicals
Estimated Purity98.00%
Molecular Weight357.4
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Overview

  • Supplier
    Biorbyt
  • Product Name
    N-Deacetylcolchicine
  • Delivery Days Customer
    10
  • CAS Number
    3476-50-4
  • Certification
    Research Use Only
  • Estimated Purity
    98.00%
  • Molecular Formula
    C20H23NO5
  • Molecular Weight
    357.4
  • Scientific Description
    Trimethylcolchicinic acid methyl ether (HAN 76504), an antimitotic agent, blocks microtubule assembly by attaching to tubulin and inhibiting its polymerization. It enhances tubulins intrinsic GTPase activity, induces apoptosis across various normal and tumor cell lines, and activates the JNK/SAPK pathway. Currently unnamed, it is referred to by a provisional code name in line with MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming) for ease of communication.
  • SMILES
    O(C)C1=C2C=3C(=CC(=O)C(OC)=CC3)[C@@H](N)CCC2=CC(OC)=C1OC
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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