N-Deacetylthiocolchicine [2731-16-0]
HY-W072781
CAS Number2731-16-0
Product group Chemicals
Molecular Weight373.47
Overview
- SupplierMedChem Express
- Product NameN-Deacetylthiocolchicine [2731-16-0]
- Delivery Days Customer999
- CAS Number2731-16-0
- CertificationResearch Use Only
- Molecular FormulaC20H23NO4S
- Molecular Weight373.47
- Scientific DescriptionN-Deacetylthiocolchicine is a tubulin inhibitor with an IC50 value of 2.2 nM in MDR-negative MDA-MB 231 breast cancer cells. N-Deacetylthiocolchicine exerts antiproliferative activity by binding to tubulin to interfere with microtubule assembly, arresting cells in mitosis during the cell cycle. N-Deacetylthiocolchicine is promising for research of malignancies such as breast cancer[1][2].
- SMILESCOC1=C(C(C([C@@H](N)CC2)=C3)=CC=C(SC)C3=O)C2=CC(OC)=C1OC
- UNSPSC12352200