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N-Deschlorobenzoyl indomethacin [2882-15-7]

HY-W008567
MedChem Express
CAS Number2882-15-7
Product group Chemicals
Estimated Purity97.0
Molecular Weight219.24
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Overview

  • Supplier
    MedChem Express
  • Product Name
    N-Deschlorobenzoyl indomethacin [2882-15-7]
  • Delivery Days Customer
    5
  • CAS Number
    2882-15-7
  • Certification
    Research Use Only
  • Estimated Purity
    97.0
  • Molecular Formula
    C12H13NO3
  • Molecular Weight
    219.24
  • Scientific Description
    N-Deschlorobenzoyl indomethacin (Compound 18), the primary metabolite of indomethacin (HY-14397), lacks the N-p-chlorobenzoyl group in its structure. Consequently, N-Deschlorobenzoyl indomethacin loses inhibitory activity against AKR1C2 and AKR1C3 (AKR1C2 IC50 =100 microM, AKR1C3 IC50 >100 microM), exhibiting no selectivity[1].
  • SMILES
    CC(N1)=C(C2=C1C=CC(OC)=C2)CC(O)=O
  • Storage Instruction
    RT
  • UNSPSC
    12352200