N-Deschlorobenzoyl indomethacin-d3

MedChem Express

N-Deschlorobenzoyl indomethacin-d3

999

Research Use Only

C12H10D3NO3

222.26

N-Deschlorobenzoyl indomethacin-d3 is the deuterium labeled N-Deschlorobenzoyl indomethacin (HY-W008567). N-Deschlorobenzoyl indomethacin (Compound 18), the primary metabolite of indomethacin (HY-14397), lacks the N-p-chlorobenzoyl group in its structure. Consequently, N-Deschlorobenzoyl indomethacin loses inhibitory activity against AKR1C2 and AKR1C3 (AKR1C2 IC50 =100 microM, AKR1C3 IC50 >100 microM), exhibiting no selectivity[1].

CC(NC1=C2C=C(OC([2H])([2H])[2H])C=C1)=C2CC(O)=O

12352200