N-Desmethyl apalutamide-d4
HY-W754151
Overview
- SupplierMedChem Express
- Product NameN-Desmethyl apalutamide-d4
- Delivery Days Customer14
- CertificationResearch Use Only
- Estimated Purity99.63
- Molecular FormulaC20H9D4F4N5O2S
- Molecular Weight467.43
- Scientific DescriptionN-Desmethyl apalutamide-d 4 is the deuterium-labeled N-Desmethyl-Apalutamide (HY-135331). N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma-proteins bound concentration [1] [2] [3] .
- SMILESO=C(N)C1=CC=C(N(C(N(C2=CC(C(F)(F)F)=C(C#N)N=C2)C3=O)=S)C43C([2H])([2H])CC4([2H])[2H])C=C1F
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200