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N-Desmethyl apalutamide-d4

HY-W754151
MedChem Express
Estimated Purity99.63
Product group Chemicals
Molecular Weight467.43
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Overview

  • Supplier
    MedChem Express
  • Product Name
    N-Desmethyl apalutamide-d4
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Estimated Purity
    99.63
  • Molecular Formula
    C20H9D4F4N5O2S
  • Molecular Weight
    467.43
  • Scientific Description
    N-Desmethyl apalutamide-d 4 is the deuterium-labeled N-Desmethyl-Apalutamide (HY-135331). N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma-proteins bound concentration [1] [2] [3] .
  • SMILES
    O=C(N)C1=CC=C(N(C(N(C2=CC(C(F)(F)F)=C(C#N)N=C2)C3=O)=S)C43C([2H])([2H])CC4([2H])[2H])C=C1F
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200