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N-Desmethyl rosiglitazone [257892-31-2]

HY-118788
MedChem Express
CAS Number257892-31-2
Product group Chemicals
Molecular Weight343.40
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Overview

  • Supplier
    MedChem Express
  • Product Name
    N-Desmethyl rosiglitazone [257892-31-2]
  • Delivery Days Customer
    5
  • CAS Number
    257892-31-2
  • Certification
    Research Use Only
  • Molecular Formula
    C17H17N3O3S
  • Molecular Weight
    343.40
  • Scientific Description
    N-Desmethyl rosiglitazone (SB 237216) is a metabolite of Rosiglitazone (HY-17386), generated through demethylation by the cytochrome P450 enzyme system in liver microsomes. It retains partial PPARgamma agonist activity and supports studies on the metabolism and pharmacokinetics of Rosiglitazone (HY-17386)[1].
  • SMILES
    O=C1SC(CC2=CC=C(C=C2)OCCNC3=NC=CC=C3)C(N1)=O
  • UNSPSC
    12352200