Chemical Structure
Chemical Structure
N-Dodecanoyl-DL-homoserine lactone [18627-38-8]
CDX-D0339
CAS Number18627-38-8
Product group Chemicals
Estimated Purity>97%
Molecular Weight283.4
Overview
- SupplierChemodex
- Product NameN-Dodecanoyl-DL-homoserine lactone [18627-38-8]
- Delivery Days Customer10
- CAS Number18627-38-8
- CertificationResearch Use Only
- Estimated Purity>97%
- Molecular FormulaC16H29NO3
- Molecular Weight283.4
- Scientific DescriptionChemical. CAS: 18627-38-8. Formula: C16H29NO3. MW: 283.4. Synthetic. N-Dodecanoyl-DL-homoserine lactone (C12-HSL) is a small diffusible signalling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria. In addition to regulating bacterial functions, C12-HSL activates NF-kappaB in RAW 264.7 macrophages, increasing the expression of TNF-alpha, interleukin-1beta (IL-1beta) and IL-8, while other lactones do not. In addition, C12-HSL alters cell cycling and metabolism of human keratinocyte (HaCaT) cells. It also was shown to induce cell death by apoptosis. - N-Dodecanoyl-DL-homoserine lactone (C12-HSL) is a small diffusible signalling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria. In addition to regulating bacterial functions, C12-HSL activates NF-kappaB in RAW 264.7 macrophages, increasing the expression of TNF-alpha, interleukin-1beta (IL-1beta) and IL-8, while other lactones do not. In addition, C12-HSL alters cell cycling and metabolism of human keratinocyte (HaCaT) cells. It also was shown to induce cell death by apoptosis.
- SMILESCCCCCCCCCCCC(=O)NC1CCOC1=O
- Storage Instruction2°C to 8°C
- UNSPSC12352200