
IHC-P analysis of human brain tissue using GTX81475 n-Myc antibody, C-term.
n-Myc antibody, C-term
GTX81475
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetMYCN
Overview
- SupplierGeneTex
- Product Namen-Myc antibody, C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4613
- Target nameMYCN
- Target descriptionMYCN proto-oncogene, bHLH transcription factor
- Target synonymsbHLHe37; class E basic helix-loop-helix protein 37; MODED; neuroblastoma MYC oncogene; neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene; NMYC; N-myc; N-myc proto-oncogene protein; ODED; oncogene NMYC; v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
- HostRabbit
- IsotypeIgG
- Protein IDP04198
- Protein NameN-myc proto-oncogene protein
- Scientific DescriptionThis gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- TRIM8 restores p53 tumour suppressor function by blunting N-MYC activity in chemo-resistant tumours. Mastropasqua F et al., 2017 Mar 21, Mol CancerRead more