Chemical Structure
Chemical Structure
N-tert-Butyl-alpha-phenylnitrone [PBN] [3376-24-7]
CDX-B0269
Product group Molecular Biology
Overview
- SupplierChemodex
- Product NameN-tert-Butyl-alpha-phenylnitrone [PBN] [3376-24-7]
- Delivery Days Customer2
- CAS Number3376-24-7
- CertificationResearch Use Only
- Estimated Purity>98%
- Molecular FormulaC11H15NO
- Molecular Weight177.2
- Scientific DescriptionCell permeable spin trap commonly used in free radical research for both in vivo and in vitro studies. It protects against oxidative damage caused by various inflammatory events, demonstrating neuroprotective, anti-anging, and antidiabetic effects. PBN has been shown to inhibit LPS-induced NF-kappaB DNA binding activity, inhibit COX-2 catalytic activity, inhibit lipid peroxidation in rat liver microsomes and prevent the induction of inducible nitric oxide synthase (iNOS). Shows anti-cancer activity in several experimental cancer models. - Chemical. CAS: 3376-24-7. Formula: C11H15NO. MW: 177.2. Synthetic. Cell permeable spin trap commonly used in free radical research for both in vivo and in vitro studies. It protects against oxidative damage caused by various inflammatory events, demonstrating neuroprotective, anti-anging, and antidiabetic effects. PBN has been shown to inhibit LPS-induced NF-kappaB DNA binding activity, inhibit COX-2 catalytic activity, inhibit lipid peroxidation in rat liver microsomes and prevent the induction of inducible nitric oxide synthase (iNOS). Shows anti-cancer activity in several experimental cancer models.
- SMILESCC(C)(C)[N+](\[O-])=C\C1=CC=CC=C1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41115800