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Chemical Structure
Chemical Structure
Chemical Structure

N-tert-Butyl-alpha-phenylnitrone [PBN]

Research Use Only
CDX-B0269
Chemodex
Product group Molecular Biology
Price on request
Packing Size
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Overview

  • Supplier
    Chemodex
  • Product Name
    N-tert-Butyl-alpha-phenylnitrone [PBN] [3376-24-7]
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Scientific Description
    Cell permeable spin trap commonly used in free radical research for both in vivo and in vitro studies. It protects against oxidative damage caused by various inflammatory events, demonstrating neuroprotective, anti-anging, and antidiabetic effects. PBN has been shown to inhibit LPS-induced NF-kappaB DNA binding activity, inhibit COX-2 catalytic activity, inhibit lipid peroxidation in rat liver microsomes and prevent the induction of inducible nitric oxide synthase (iNOS). Shows anti-cancer activity in several experimental cancer models. - Chemical. CAS: 3376-24-7. Formula: C11H15NO. MW: 177.2. Synthetic. Cell permeable spin trap commonly used in free radical research for both in vivo and in vitro studies. It protects against oxidative damage caused by various inflammatory events, demonstrating neuroprotective, anti-anging, and antidiabetic effects. PBN has been shown to inhibit LPS-induced NF-kappaB DNA binding activity, inhibit COX-2 catalytic activity, inhibit lipid peroxidation in rat liver microsomes and prevent the induction of inducible nitric oxide synthase (iNOS). Shows anti-cancer activity in several experimental cancer models.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    41116133