N3-C3-NHS ester [943858-70-6]

MedChem Express

N3-C3-NHS ester [943858-70-6]

10

943858-70-6

Research Use Only

99.85

C8H10N4O4

226.19

N3-C3-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(ON1C(CCC1=O)=O)CCCN=[N+]=[N-]

-20°C

41115800