N3-C4-NHS ester [478801-48-8]

MedChem Express

N3-C4-NHS ester [478801-48-8]

10

478801-48-8

Research Use Only

99.53

C9H12N4O4

240.22

N3-C4-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(ON1C(CCC1=O)=O)CCCCN=[N+]=[N-]

-20°C

41115800