N3-Ph-NHS ester [53053-08-0]

MedChem Express

N3-Ph-NHS ester [53053-08-0]

10

53053-08-0

Research Use Only

99.88

C11H8N4O4

260.21

N3-Ph-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-Ph-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(ON1C(CCC1=O)=O)C2=CC=C(N=[N+]=[N-])C=C2

-20°C,2°C to 8°C

41115800