N4-(n-Palmitoyl)-4-azido-2-deoxy-2-fluoro-arabinocytidine

MedChem Express

N4-(n-Palmitoyl)-4-azido-2-deoxy-2-fluoro-arabinocytidine

10

Research Use Only

C25H41FN6O5

524.63

N4-(n-Palmitoyl)-4-azido-2-deoxy-2-fluoro-arabinocytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1]. N4-(n-Palmitoyl)-4-azido-2-deoxy-2-fluoro-arabinocytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C1N([C@H]2[C@@H](F)[C@H](O)[C@](CO)(N=[N+]=[N-])O2)C=CC(NC(CCCCCCCCCCCCCCC)=O)=N1

41115811