NABP1 Antibody, HRP conjugated

Cusabio

NABP1 Antibody, HRP conjugated

20

ELISA

Research Use Only

Polyclonal

HRP

NABP1

nucleic acid binding protein 1

OBFC2A; oligonucleotide/oligosaccharide-binding fold containing 2A; oligonucleotide/oligosaccharide-binding fold-containing protein 2A; sensor of single-strand DNA complex subunit B2; sensor of ssDNA subunit B2; single-stranded DNA-binding protein 2; SOSS complex subunit B2; SOSS-B2; SSB2

Rabbit

IgG

SOSS complex subunit B2

Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.

Human

-20°C or -80°C

12352203