NAE-IN-M22

MedChem Express

NAE-IN-M22 [864420-54-2]

10

864420-54-2

Research Use Only

99.94

C20H24Cl2N2

363.32

NAE-IN-M22 is a potent, selective and reversible inhibitor of NEDD8 activating enzyme (NAE), with potency in micromolar range. NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can inhibit tumor growth in vivo[1].

ClC1=CC=C(CCNC2CCN(CC3=CC=CC=C3)CC2)C(Cl)=C1

-20°C,2°C to 8°C

12352200