Naftifine hydrochloride [65473-14-5]
T1543
CAS Number65473-14-5
Product group Chemicals
Estimated Purity99.76%
Molecular Weight323.86
Overview
- SupplierTargetMol Chemicals
- Product NameNaftifine hydrochloride [65473-14-5]
- Delivery Days Customer4
- CAS Number65473-14-5
- CertificationResearch Use Only
- Chemical NameNaftifine hydrochloride
- Estimated Purity99.76%
- Molecular FormulaC21H22ClN
- Molecular Weight323.86
- Scientific DescriptionNaftifine Hydrochloride is the hydrochloride salt form of naftifine, an allylamine derivate with synthetic broad-spectrum antifungal activity. Although the exact mechanism through which naftifine hydrochloride exerts its effect is unknown, it appears to selectively inhibit the enzyme squalene 2, 3-epoxidase, thereby inhibiting the biosynthesis of sterol. This results in a decreased amount of sterols, especially ergosterol which is the primary fungal membrane sterol, and a corresponding accumulation of squalene in fungal cells. Naftifine hydrochloride (Naftifine HCl) can be fungicidal as well as fungistatic to yeasts depending on the concentration and the organisms involved.
- Shelf life instruction3 years
- SMILESCl.CN(C\C=C\c1ccccc1)Cc1cccc2ccccc12
- Storage Instruction-20°C
- UNSPSC12352200
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