The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA089095(NAIF1 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA089095(NAIF1 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200)
NAIF1 Antibody
CSB-PA089095
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetNAIF1
Overview
- SupplierCusabio
- Product NameNAIF1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID203245
- Target nameNAIF1
- Target descriptionnuclear apoptosis inducing factor 1
- Target synonymsbA379C10.2; C9orf90; nuclear apoptosis-inducing factor 1
- HostRabbit
- IsotypeIgG
- Protein IDQ69YI7
- Protein NameNuclear apoptosis-inducing factor 1
- Scientific DescriptionHuman NAIF1 is located on chromosome 9q34.11 and encodes 327 amino acids with a homeodomain-like region and two nuclear localization signals at its N-terminal region. NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken and frog, and shares no obvious homology to any known genes or proteins. NAIF1 was predominantly localized in the nucleus. Overexpression of NAIF1 inhibited cell growth and induced apoptosis. Furthermore, NAIF1 transfection caused both decreases in mitochondrial membrane potential and caspase-3 activation. In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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