NAK / TBK1 antibody [108A429]

GeneTex

NAK / TBK1 antibody [108A429]

9

WB: 1 - 2 microg/ml. ICC/IF: 1:20. IHC-P: 1:20 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

108A429

1 mg/ml

Unconjugated

TBK1

TANK binding kinase 1

AIARV, FTDALS4, IIAE8, NAK, T2K, serine/threonine-protein kinase TBK1, NF-kB-activating kinase, NF-kappa-B-activating kinase

Mouse

IgG1

Serine/threonine-protein kinase TBK1

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK. [provided by RefSeq]

Bovine, Canine, Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203