NALP5 antibody

GeneTex

NALP5 antibody

9

WB: 1 microg/mL. IHC-P: 10 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

NLRP5

NLR family pyrin domain containing 5

CLR19.8, MATER, NALP5, OZEMA19, PAN11, PYPAF8, NACHT, LRR and PYD domains-containing protein 5, NACHT, leucine rich repeat and PYD containing 5, mater protein homolog, maternal antigen that embryos require, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5

Rabbit

IgG

NACHT, LRR and PYD domains-containing protein 5

NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203