Namoline [342795-11-3]

MedChem Express

Namoline [342795-11-3]

10

342795-11-3

Research Use Only

C10H3ClF3NO4

293.58

Namoline, a gamma-pyrone, is a selective and reversible Lysine-specific demethylase 1 (LSD1) inhibitor with an IC50 of 51 microM in a HRP-coupled enzymatic assay. Namoline impairs LSD1 demethylase activity and blocks cell proliferation. Namoline has the potential for androgen-dependent prostate cancer research[1].

O=C1C(Cl)=C(C(F)(F)F)OC2=CC=C([N+]([O-])=O)C=C12

12352200