Bio-Connect

Nampt-IN-10 (trihydrochloride)

HY-147193A
MedChem Express
Molecular Weight582.92
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Nampt-IN-10 (trihydrochloride)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C27H31Cl3FN5O2
  • Molecular Weight
    582.92
  • Scientific Description
    Nampt-IN-10 trihydrochloride (compound 4) is a Nicotinamide Phosphoribosyltransferase (NAMPT) inhibitor. Nampt-IN-10 trihydrochloride shows cellular potency to A2780 and CORL23 cell lines with IC50 values of 5 and 19 nM, respectively. Nampt-IN-10 trihydrochloride can be used as a novel non-antimitotic payload for antibody-drug conjugate (ADC)[1].
  • SMILES
    FC(C=C1NC([C@@H]2[C@@H](C3=CN=CC=C3)C2)=O)=C(C=C1)CNC(C4=CC=C(N5CCNCC5)C=C4)=O.[H]Cl.[H]Cl.[H]Cl
  • UNSPSC
    12131703