Nampt-IN-8 [2453183-75-8]

MedChem Express

Nampt-IN-8 [2453183-75-8]

10

2453183-75-8

Research Use Only

C36H35N3O4

573.68

Nampt-IN-8 (Compound 10d) is an NAMPT inhibitor with an IC50 of 0.183 microM. Nampt-IN-8 is also a relatively good NQO1 substrate. Nampt-IN-8 induces cell apoptosis and ROS[1].

O=C1C2=C(CCCC3(C)C)C3=CC=C2C4=C(C1=O)C(C)=C(O4)CNC5=CC=C(C=C5)CCNC(/C=C/C6=CN=CC=C6)=O

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